A new COVID-19 variant, KP.3, is rapidly spreading across the United States, raising concerns about a potential summer surge. Scientists are closely monitoring these FLiRT strains, which now account for over half of all infections. With vaccines still providing some protection, the evolving landscape of the pandemic demands our attention.
New COVID-19 Variant Emerges

A new COVID-19 variant, KP.3, has recently become dominant in the United States. This variant belongs to a family of mutated strains known as “FLiRT,” driving an increasing number of cases nationwide.
FLiRT strains, including KP.3, KP.2, and KP.1.1, now account for over half of all COVID-19 infections across the country. The latest CDC data highlights the significant presence of these variants.
Evolution of FLiRT Variants

The FLiRT variants, named for their spike protein mutations, have been present in the U.S. since early spring. In April, KP.2 rapidly surpassed JN.1, the omicron subvariant responsible for last winter’s surge.
Within weeks, KP.3 overtook KP.2 to become the most prevalent strain in the U.S. CDC reports indicate its swift rise in the viral hierarchy.
Rising Cases of KP.3

From early May to June 8, KP.3’s prevalence jumped from 9% to 25% of U.S. cases. KP.2 follows closely, accounting for about 22% of cases, with LB.1 and KP.1.1 trailing.
FLiRT variants collectively represent an estimated 55% of U.S. COVID-19 cases. Despite low hospitalization rates, a slight increase in test positivity and emergency room visits has been observed.
Potential Summer Surge

Concerns about a summer wave are rising as FLiRT variants may evade the immune system more effectively. Scientists cite waning immunity and low vaccine uptake as contributing factors.
The Name “FLiRT”

The FLiRT name is derived from the technical names of their mutations. These variants are part of the omicron family, similar to other dominant strains from the past year.
The Cycle of Variants

The emergence of KP.3 mirrors previous patterns of SARS-CoV-2 evolution. New variants frequently arise, becoming dominant much faster than other viruses like influenza.
Initial observations suggest that KP.3 is highly transmissible. The increasing proportion of KP.3 cases indicates its competitive advantage over other variants.
Immunity and Protection

Over 97% of the U.S. population has some form of immunity against SARS-CoV-2. However, waning immunity and low vaccination rates could allow FLiRT variants to spread more easily.
Current State of COVID-19

KP.3 and FLiRT variants may or may not cause a significant summer surge, according to experts. What is clear is that COVID-19 remains present and active across the United States.
Infections are occurring throughout the year, with varying levels of intensity. Despite low overall numbers, test positivity has increased slightly, suggesting continued viral activity.
Decline in Testing Rates

COVID-19 testing, particularly PCR tests, has decreased, making tracking difficult. Many individuals test at home without reporting, contributing to underreported case numbers.
Hospitalizations and Wastewater Data

Hospitalizations remain low, offering some reassurance. Wastewater data from the CDC indicates low viral activity, a significant drop from the high levels observed earlier this year.
Integration into Daily Life

COVID-19 is becoming a permanent part of life, with its seasonal patterns still under study. Experts stress the importance of ongoing caution and data monitoring.
Symptoms of KP.3 and other FLiRT variants are similar to those of previous strains. These include sore throat, cough, fatigue, congestion, headache, and more. Current tests detect KP.3 and other FLiRT variants effectively. Antivirals like Paxlovid remain effective, with no significant signs of resistance emerging.
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